Needle jets often wear oval, so eyeballing this will often show a less than round shape shall we say.
Just comparing/trying new ones will often show an improvement in fuel economy, if you are patient enough to record such stuff.
If one pipe is sootier than the other, and you have a single carb bike (it sounds like it ?, not knowing your bike personally),
oil burning can also produce a sooty exhaust. Unless it is chronic, the difference between dry soot and oily soot can be tough to spot..
Doing a compression test on both cylinders (hot, throttle wide open) may show something, although this may not detect one poor oil ring for example.