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This bike is a DKW E 250 build in 1927 or 1928, these are the only two years this model was build. It has a 250 cc two-stroke engine and is fan cooled. The gearbox is a three speed from Hirth, a German make. DKW's were build in the city of Zschopau in Saxony. After the latest war the MZ motorcycles came from this same factory. The registration number comes also from the province of Saxony. I am sure about this bike because I own one myself.
Thanks also to Wieber Brouwer for his email that said